8 Session information

## R version 4.5.1 (2025-06-13)
## Platform: aarch64-apple-darwin20
## Running under: macOS Sequoia 15.5
## 
## Matrix products: default
## BLAS:   /Library/Frameworks/R.framework/Versions/4.5-arm64/Resources/lib/libRblas.0.dylib 
## LAPACK: /Library/Frameworks/R.framework/Versions/4.5-arm64/Resources/lib/libRlapack.dylib;  LAPACK version 3.12.1
## 
## locale:
## [1] C/UTF-8/C/C/C/C
## 
## time zone: Asia/Shanghai
## tzcode source: internal
## 
## attached base packages:
## [1] stats4    grid      stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] export_0.3.0           openxlsx_4.2.8         drc_3.0-1             
##  [4] MASS_7.3-65            circlize_0.4.16        ComplexHeatmap_2.24.1 
##  [7] plyr_1.8.9             GOplot_1.0.2           gridExtra_2.3         
## [10] ggdendro_0.2.0         forestploter_1.1.3     WGCNA_1.73            
## [13] fastcluster_1.3.0      dynamicTreeCut_1.63-1  BiocParallel_1.42.1   
## [16] GSEABase_1.70.0        graph_1.86.0           annotate_1.86.1       
## [19] XML_3.99-0.18          GSVA_2.2.0             msigdbr_25.1.0        
## [22] limma_3.64.1           org.Hs.eg.db_3.21.0    AnnotationDbi_1.70.0  
## [25] IRanges_2.42.0         S4Vectors_0.46.0       Biobase_2.68.0        
## [28] BiocGenerics_0.54.0    generics_0.1.4         clusterProfiler_4.16.0
## [31] pheatmap_1.0.13        survminer_0.5.0        survival_3.8-3        
## [34] colorRamp2_0.1.0       SNFtool_2.3.1          ggrepel_0.9.6         
## [37] reshape2_1.4.4         ggpubr_0.6.1           ggunchained_0.0.1     
## [40] devtools_2.4.5         usethis_3.1.0          RColorBrewer_1.1-3    
## [43] umap_0.2.10.0          vioplot_0.5.1          zoo_1.8-14            
## [46] sm_2.2-6.0             corrplot_0.95          readxl_1.4.5          
## [49] VennDiagram_1.7.3      futile.logger_1.4.3    lubridate_1.9.4       
## [52] forcats_1.0.0          stringr_1.5.1          dplyr_1.1.4           
## [55] purrr_1.0.4            readr_2.1.5            tidyr_1.3.1           
## [58] tibble_3.3.0           ggplot2_3.5.2          tidyverse_2.0.0       
## 
## loaded via a namespace (and not attached):
##   [1] SpatialExperiment_1.18.1    R.methodsS3_1.8.2          
##   [3] dichromat_2.0-0.1           prettyGraphs_2.2.0         
##   [5] urlchecker_1.0.1            nnet_7.3-20                
##   [7] Biostrings_2.76.0           HDF5Array_1.36.0           
##   [9] TH.data_1.1-3               vctrs_0.6.5                
##  [11] ggtangle_0.0.7              digest_0.6.37              
##  [13] png_0.1-8                   shape_1.4.6.1              
##  [15] magick_2.8.7                fontLiberation_0.1.0       
##  [17] httpuv_1.6.16               foreach_1.5.2              
##  [19] qvalue_2.40.0               withr_3.0.2                
##  [21] xfun_0.52                   ggfun_0.1.9                
##  [23] ellipsis_0.3.2              memoise_2.0.1              
##  [25] gson_0.1.0                  profvis_0.4.0              
##  [27] systemfonts_1.2.3           ragg_1.4.0                 
##  [29] tidytree_0.4.6              GlobalOptions_0.1.2        
##  [31] gtools_3.9.5                R.oo_1.27.1                
##  [33] Formula_1.2-5               KEGGREST_1.48.1            
##  [35] promises_1.3.3              httr_1.4.7                 
##  [37] rstatix_0.7.2               rhdf5filters_1.20.0        
##  [39] rhdf5_2.52.1                rstudioapi_0.17.1          
##  [41] UCSC.utils_1.4.0            miniUI_0.1.2               
##  [43] DOSE_4.2.0                  base64enc_0.1-3            
##  [45] babelgene_22.9              curl_6.4.0                 
##  [47] ScaledMatrix_1.16.0         h5mread_1.0.1              
##  [49] GenomeInfoDbData_1.2.14     SparseArray_1.8.0          
##  [51] xtable_1.8-4                doParallel_1.0.17          
##  [53] evaluate_1.0.4              S4Arrays_1.8.1             
##  [55] preprocessCore_1.70.0       hms_1.1.3                  
##  [57] GenomicRanges_1.60.0        bookdown_0.43              
##  [59] irlba_2.3.5.1               colorspace_2.1-1           
##  [61] reticulate_1.42.0           magrittr_2.0.3             
##  [63] later_1.4.2                 ggtree_3.16.0              
##  [65] lattice_0.22-7              cowplot_1.1.3              
##  [67] matrixStats_1.5.0           Hmisc_5.2-3                
##  [69] pillar_1.11.0               nlme_3.1-168               
##  [71] iterators_1.0.14            compiler_4.5.1             
##  [73] beachmat_2.24.0             RSpectra_0.16-2            
##  [75] stringi_1.8.7               SummarizedExperiment_1.38.1
##  [77] crayon_1.5.3                abind_1.4-8                
##  [79] gridGraphics_0.5-1          bit_4.6.0                  
##  [81] sandwich_3.1-1              fastmatch_1.1-6            
##  [83] textshaping_1.0.1           codetools_0.2-20           
##  [85] multcomp_1.4-28             BiocSingular_1.24.0        
##  [87] openssl_2.3.3               flextable_0.9.9            
##  [89] bslib_0.9.0                 GetoptLong_1.0.5           
##  [91] mime_0.13                   splines_4.5.1              
##  [93] Rcpp_1.1.0                  sparseMatrixStats_1.20.0   
##  [95] cellranger_1.1.0            Rttf2pt1_1.3.12            
##  [97] knitr_1.50                  blob_1.2.4                 
##  [99] clue_0.3-66                 fs_1.6.6                   
## [101] checkmate_2.3.2             pkgbuild_1.4.8             
## [103] ggsignif_0.6.4              ggplotify_0.1.2            
## [105] Matrix_1.7-3                statmod_1.5.0              
## [107] tzdb_0.5.0                  pkgconfig_2.0.3            
## [109] tools_4.5.1                 cachem_1.1.0               
## [111] stargazer_5.2.3             RSQLite_2.4.1              
## [113] DBI_1.2.3                   impute_1.82.0              
## [115] fastmap_1.2.0               rmarkdown_2.29             
## [117] scales_1.4.0                officer_0.6.10             
## [119] broom_1.0.8                 sass_0.4.10                
## [121] patchwork_1.3.1             carData_3.0-5              
## [123] rpart_4.1.24                farver_2.1.2               
## [125] ExPosition_2.11.0           yaml_2.3.10                
## [127] MatrixGenerics_1.20.0       foreign_0.8-90             
## [129] ggthemes_5.1.0              cli_3.6.5                  
## [131] lifecycle_1.0.4             askpass_1.2.1              
## [133] mvtnorm_1.3-3               lambda.r_1.2.4             
## [135] sessioninfo_1.2.3           backports_1.5.0            
## [137] timechange_0.3.0            gtable_0.3.6               
## [139] rjson_0.2.23                devEMF_4.5-1               
## [141] parallel_4.5.1              ape_5.8-1                  
## [143] jsonlite_2.0.0              bit64_4.6.0-1              
## [145] assertthat_0.2.1            yulab.utils_0.2.0          
## [147] zip_2.3.3                   futile.options_1.0.1       
## [149] jquerylib_0.1.4             GOSemSim_2.34.0            
## [151] survMisc_0.5.6              R.utils_2.13.0             
## [153] lazyeval_0.2.2              rgl_1.3.24                 
## [155] shiny_1.11.1                htmltools_0.5.8.1          
## [157] enrichplot_1.28.2           rvg_0.3.5                  
## [159] KMsurv_0.1-6                GO.db_3.21.0               
## [161] alluvial_0.1-2              formatR_1.14               
## [163] glue_1.8.0                  XVector_0.48.0             
## [165] gdtools_0.4.2               treeio_1.32.0              
## [167] extrafontdb_1.0             igraph_2.1.4               
## [169] R6_2.6.1                    SingleCellExperiment_1.30.1
## [171] km.ci_0.5-6                 cluster_2.1.8.1            
## [173] pkgload_1.4.0               Rhdf5lib_1.30.0            
## [175] aplot_0.2.8                 GenomeInfoDb_1.44.0        
## [177] plotrix_3.8-4               DelayedArray_0.34.1        
## [179] tidyselect_1.2.1            htmlTable_2.4.3            
## [181] xml2_1.3.8                  fontBitstreamVera_0.1.1    
## [183] car_3.1-3                   rsvd_1.0.5                 
## [185] fontquiver_0.2.1            data.table_1.17.6          
## [187] htmlwidgets_1.6.4           fgsea_1.34.0               
## [189] rlang_1.1.6                 extrafont_0.19             
## [191] uuid_1.2-1                  remotes_2.5.0