group	onto	namespace	name	pvalue	adjp	zscore	or	CIl	CIu	distance	nA	nO	overlap
leading	KEGG	Environmental Process	Cytokine-cytokine receptor interaction	7.999999999999998e-138	8.399999999999998e-136	51.6	78.7	57.8	108	3	287	114	CCL1, CCL11, CCL13, CCL15, CCL16, CCL17, CCL18, CCL19, CCL2, CCL20, CCL21, CCL22, CCL24, CCL25, CCL26, CCL27, CCL3, CCL3L3, CCL4L1, CCL5, CCL7, CCL8, CCR1, CCR10, CCR2, CCR3, CCR5, CCR6, CCR7, CCR8, CCR9, CD4, CSF2, CSF3, CX3CL1, CX3CR1, CXCL1, CXCL10, CXCL11, CXCL12, CXCL13, CXCL14, CXCL16, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, CXCL9, CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, CXCR6, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNAR1, IFNAR2, IFNB1, IFNE, IFNG, IFNGR1, IFNGR2, IFNK, IFNL1, IFNL2, IFNL3, IFNLR1, IFNW1, IL10, IL10RA, IL10RB, IL12A, IL12B, IL12RB1, IL12RB2, IL13, IL15, IL18, IL1A, IL1B, IL1RN, IL2, IL20RA, IL22RA1, IL23R, IL2RA, IL2RB, IL2RG, IL3RA, IL4, IL4R, IL5, IL6, IL6R, IL7R, LIF, PF4, PPBP, TNF, TNFRSF1B, XCL1, XCL2, XCR1
leading	KEGG	Environmental Process	Viral protein interaction with cytokine and cytokine receptor	1.3999999999999996e-105	4.999999999999999e-104	54.7	220	136	370	3	96	69	CCL1, CCL11, CCL13, CCL15, CCL16, CCL17, CCL18, CCL19, CCL2, CCL20, CCL21, CCL22, CCL24, CCL25, CCL26, CCL27, CCL3, CCL3L3, CCL4L1, CCL5, CCL7, CCL8, CCR1, CCR10, CCR2, CCR3, CCR5, CCR6, CCR7, CCR8, CCR9, CX3CL1, CX3CR1, CXCL1, CXCL10, CXCL11, CXCL12, CXCL13, CXCL14, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, CXCL9, CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, IL10, IL10RA, IL10RB, IL18, IL2, IL20RA, IL22RA1, IL2RA, IL2RB, IL2RG, IL6, IL6R, PF4, PPBP, TNF, TNFRSF1B, XCL1, XCL2, XCR1
leading	KEGG	Organismal System	Chemokine signaling pathway	9.599999999999998e-97	2.4999999999999996e-95	44.7	68.5	48.5	96.9	3	188	80	ARRB1, ARRB2, CCL1, CCL11, CCL13, CCL15, CCL16, CCL17, CCL18, CCL19, CCL2, CCL20, CCL21, CCL22, CCL24, CCL25, CCL26, CCL27, CCL3, CCL3L3, CCL4L1, CCL5, CCL7, CCL8, CCR1, CCR10, CCR2, CCR3, CCR5, CCR6, CCR7, CCR8, CCR9, CX3CL1, CX3CR1, CXCL1, CXCL10, CXCL11, CXCL12, CXCL13, CXCL14, CXCL16, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, CXCL9, CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, CXCR6, GNAI1, GNAI2, GNAI3, GNAQ, GNB1, GNG2, HCK, ITK, JAK2, JAK3, LYN, PF4, PIK3CA, PIK3R1, PLCG1, PPBP, SHC1, SRC, STAT1, STAT2, STAT3, STAT5B, VAV1, XCL1, XCL2, XCR1
leading	KEGG	Environmental Process	JAK-STAT signaling pathway	1.1999999999999999e-84	2.499999999999999e-83	42.1	66	45.9	95.1	3	162	70	CSF2, CSF3, EGFR, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNAR1, IFNAR2, IFNB1, IFNE, IFNG, IFNGR1, IFNGR2, IFNK, IFNL1, IFNL2, IFNL3, IFNLR1, IFNW1, IL10, IL10RA, IL10RB, IL12A, IL12B, IL12RB1, IL12RB2, IL13, IL15, IL2, IL20RA, IL22RA1, IL22RA2, IL23R, IL2RA, IL2RB, IL2RG, IL3RA, IL4, IL4R, IL5, IL6, IL6R, IL7R, IRF9, JAK1, JAK2, JAK3, LIF, PIK3CA, PIK3R1, PTPN11, PTPN6, SOCS1, SOCS3, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6, TYK2
leading	KEGG	Organismal System	Th1 and Th2 cell differentiation	2.7e-61	4.0000000000000004e-60	38.1	83	52.3	133	3	90	47	CD247, CD3D, CD3E, CD3G, CD4, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5, IFNG, IFNGR1, IFNGR2, IL12A, IL12B, IL12RB1, IL12RB2, IL13, IL2, IL2RA, IL2RB, IL2RG, IL4, IL4R, IL5, JAK1, JAK2, JAK3, JUN, LCK, PLCG1, PRKCQ, STAT1, STAT4, STAT5A, STAT5B, STAT6, TBX21, TYK2, ZAP70
leading	KEGG	Organismal System	Th17 cell differentiation	7.299999999999999e-57	9.499999999999997e-56	35	60.4	39.2	92.9	3	106	47	CD247, CD3D, CD3E, CD3G, CD4, FOXP3, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5, IFNG, IFNGR1, IFNGR2, IL12RB1, IL1B, IL2, IL23R, IL2RA, IL2RB, IL2RG, IL4, IL4R, IL6, IL6R, JAK1, JAK2, JAK3, JUN, LCK, PLCG1, PRKCQ, STAT1, STAT3, STAT5A, STAT5B, STAT6, TBX21, TYK2, ZAP70
leading	KEGG	Organismal System	Natural killer cell mediated cytotoxicity	5e-39	2.0999999999999999e-38	26	33.1	21.3	50.5	3	121	38	CD247, CSF2, FYN, HLA-A, HLA-B, HLA-C, HLA-E, HLA-G, ICAM1, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNAR1, IFNAR2, IFNB1, IFNG, IFNGR1, IFNGR2, LCK, LCP2, PIK3CA, PIK3R1, PLCG1, PTPN11, PTPN6, SH3BP2, SHC1, TNF, VAV1, ZAP70
leading	KEGG	Organismal System	Toll-like receptor signaling pathway	2.9e-38	1.2e-37	26.8	39.6	24.8	62.3	3	98	35	CCL3, CCL3L3, CCL4L1, CCL5, CD80, CD86, CTSK, CXCL10, CXCL11, CXCL8, CXCL9, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNAR1, IFNAR2, IFNB1, IL12A, IL12B, IL1B, IL6, JUN, PIK3CA, PIK3R1, STAT1, TLR7, TNF
leading	KEGG	Organismal System	Intestinal immune network for IgA production	1.3e-35	4.7e-35	29.9	93.5	48.8	182	3	45	26	CCL25, CCR10, CCR9, CD28, CD80, CD86, CXCL12, CXCR4, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5, IL10, IL15, IL2, IL4, IL5, IL6
leading	KEGG	Organismal System	Antigen processing and presentation	2.3e-31	7.6e-31	25.1	46.2	26.7	79	3	67	27	B2M, CD4, CD74, CTSB, CTSL, CTSS, HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5, HLA-E, HLA-F, HLA-G, IFNG, LGMN, TNF
leading	KEGG	Organismal System	T cell receptor signaling pathway	4.7e-27	1.3e-26	20.7	26	15.8	41.7	3	102	28	CD247, CD28, CD3D, CD3E, CD3G, CD4, CSF2, FYN, GRAP2, IFNG, IL10, IL2, IL4, IL5, ITK, JUN, LCK, LCP2, PDCD1, PIK3CA, PIK3R1, PLCG1, PRKCQ, PTPN6, PTPRC, TNF, VAV1, ZAP70
leading	KEGG	Organismal System	NOD-like receptor signaling pathway	1.6000000000000002e-23	3.7e-23	16.9	14.8	9.49	22.6	3	176	31	CCL2, CCL5, CTSB, CXCL1, CXCL2, CXCL3, CXCL8, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNAR1, IFNAR2, IFNB1, IL18, IL1B, IL6, IRF9, JAK1, JUN, STAT1, STAT2, TNF, TYK2
leading	KEGG	Environmental Process	TNF signaling pathway	1.3e-21	3e-21	17.2	19	11.4	30.6	3	114	25	CCL2, CCL20, CCL5, CSF2, CX3CL1, CXCL1, CXCL10, CXCL2, CXCL3, CXCL5, CXCL6, ICAM1, IFNB1, IL15, IL1B, IL6, IRF1, JUN, LIF, MMP9, PIK3CA, PIK3R1, SOCS3, TNF, TNFRSF1B
leading	KEGG	Organismal System	IL-17 signaling pathway	3e-21	6.7e-21	17.7	22	12.9	36.5	3	93	23	CCL11, CCL17, CCL2, CCL20, CCL7, CSF2, CSF3, CXCL1, CXCL10, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, IFNG, IL13, IL1B, IL4, IL5, IL6, JUN, MMP9, TNF
leading	KEGG	Environmental Process	Cell adhesion molecules	6.2e-21	1.3e-20	16	15.1	9.34	23.7	3	149	27	CD274, CD28, CD4, CD80, CD86, HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB5, HLA-E, HLA-F, HLA-G, ICAM1, PDCD1, PDCD1LG2, PTPRC
leading	KEGG	Organismal System	RIG-I-like receptor signaling pathway	3.9e-20	8.2e-20	18	27	14.9	47.3	3	69	20	CXCL10, CXCL8, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNB1, IFNE, IFNK, IFNW1, IL12A, IL12B, TNF
leading	KEGG	Organismal System	Osteoclast differentiation	3.2e-18	6.6e-18	15	15.2	9.05	24.8	3	124	23	CTSK, FYN, IFNAR1, IFNAR2, IFNB1, IFNG, IFNGR1, IFNGR2, IL1A, IL1B, IRF9, JAK1, JUN, LCK, LCP2, PIK3CA, PIK3R1, SOCS1, SOCS3, STAT1, STAT2, TNF, TYK2
leading	KEGG	Environmental Process	PI3K-Akt signaling pathway	2.5e-17	4.9e-17	12.2	7.54	4.99	11.1	3	348	34	CSF3, EGFR, GNB1, GNG2, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNAR1, IFNAR2, IFNB1, IL2, IL2RA, IL2RB, IL2RG, IL3RA, IL4, IL4R, IL6, IL6R, IL7R, INS, JAK1, JAK2, JAK3, PIK3CA, PIK3R1
leading	KEGG	Organismal System	Cytosolic DNA-sensing pathway	3.4e-17	6.6e-17	16	22.7	12.3	40.3	3	70	18	CCL4L1, CCL5, CXCL10, IFNA1, IFNA10, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA7, IFNA8, IFNB1, IL18, IL1B, IL6
leading	KEGG	Organismal System	C-type lectin receptor signaling pathway	4.2e-14	7.1e-14	12.9	14	7.78	24	3	102	18	CCL17, CCL22, IL10, IL12A, IL12B, IL1B, IL2, IL6, IRF1, IRF9, JUN, PIK3CA, PIK3R1, PTPN11, SRC, STAT1, STAT2, TNF
leading	KEGG	Environmental Process	NF-kappa B signaling pathway	4.1e-13	6.7e-13	12.2	13.3	7.29	23.1	3	100	17	CCL13, CCL19, CCL21, CCL4L1, CXCL1, CXCL12, CXCL2, CXCL3, CXCL8, ICAM1, IL1B, LCK, LYN, PLCG1, PRKCQ, TNF, ZAP70
leading	KEGG	Organismal System	Prolactin signaling pathway	8e-11	1.2e-10	11.3	14.6	7.22	27.5	3	70	13	INS, IRF1, JAK2, PIK3CA, PIK3R1, SHC1, SOCS1, SOCS3, SRC, STAT1, STAT3, STAT5A, STAT5B
leading	KEGG	Organismal System	Fc epsilon RI signaling pathway	5.6e-10	8.1e-10	10.7	14.2	6.8	27.3	3	66	12	CSF2, FYN, IL13, IL4, IL5, LCP2, LYN, PIK3CA, PIK3R1, PLCG1, TNF, VAV1
leading	KEGG	Organismal System	Growth hormone synthesis, secretion and action	7.3e-10	1e-9	9.58	9.38	4.98	16.5	3	118	15	GNAI1, GNAI2, GNAI3, GNAQ, JAK2, PIK3CA, PIK3R1, PLCG1, SHC1, SOCS1, SOCS3, STAT1, STAT3, STAT5A, STAT5B
leading	KEGG	Organismal System	Relaxin signaling pathway	2.6e-9	3.6e-9	9.04	8.47	4.51	14.9	3	129	15	ARRB1, ARRB2, EGFR, GNAI1, GNAI2, GNAI3, GNAO1, GNB1, GNG2, JUN, MMP9, PIK3CA, PIK3R1, SHC1, SRC
leading	KEGG	Organismal System	Leukocyte transendothelial migration	3.1e-8	4.2e-8	8.4	8.38	4.24	15.3	3	112	13	CXCL12, CXCR4, GNAI1, GNAI2, GNAI3, ICAM1, ITK, MMP9, PIK3CA, PIK3R1, PLCG1, PTPN11, VAV1
leading	KEGG	Organismal System	Estrogen signaling pathway	4.8e-8	6.3e-8	8.21	8.06	4.08	14.7	3	116	13	CTSD, EGFR, GNAI1, GNAI2, GNAI3, GNAO1, GNAQ, JUN, MMP9, PIK3CA, PIK3R1, SHC1, SRC
leading	KEGG	Environmental Process	ErbB signaling pathway	1e-6	1.3e-6	7.48	8.52	3.87	16.9	3	84	10	CBL, EGFR, JUN, PIK3CA, PIK3R1, PLCG1, SHC1, SRC, STAT5A, STAT5B
leading	KEGG	Environmental Process	Rap1 signaling pathway	1.4e-6	1.8e-6	6.45	5	2.7	8.64	3	207	15	EGFR, FPR1, FYB1, GNAI1, GNAI2, GNAI3, GNAO1, GNAQ, INS, LCP2, PIK3CA, PIK3R1, PLCG1, SRC, VAV1
leading	KEGG	Environmental Process	HIF-1 signaling pathway	1.5e-6	1.9e-6	7.03	7.1	3.38	13.5	3	109	11	EGFR, IFNG, IFNGR1, IFNGR2, IL6, IL6R, INS, PIK3CA, PIK3R1, PLCG1, STAT3
leading	KEGG	Organismal System	Cholinergic synapse	2e-6	2.4e-6	6.9	6.89	3.28	13.1	3	112	11	FYN, GNAI1, GNAI2, GNAI3, GNAO1, GNAQ, GNB1, GNG2, JAK2, PIK3CA, PIK3R1
leading	KEGG	Environmental Process	Phospholipase D signaling pathway	4.5e-6	5.2e-6	6.34	5.68	2.82	10.5	3	146	12	AGT, CXCL8, CXCR1, CXCR2, EGFR, FYN, INS, PIK3CA, PIK3R1, PLCG1, PTPN11, SHC1
leading	KEGG	Organismal System	Platelet activation	3.1e-5	3.5e-5	5.74	5.57	2.56	10.8	3	123	10	FYN, GNAI1, GNAI2, GNAI3, GNAQ, LCP2, LYN, PIK3CA, PIK3R1, SRC
leading	KEGG	Organismal System	Axon guidance	1.8e-4	1.9e-4	4.78	4.07	1.97	7.62	3	181	11	CXCL12, CXCR4, FYN, GNAI1, GNAI2, GNAI3, PIK3CA, PIK3R1, PLCG1, PTPN11, SRC
leading	KEGG	Environmental Process	Ras signaling pathway	0.0044	0.0045	3.3	2.84	1.32	5.42	3	230	10	EGFR, GNB1, GNG2, INS, PIK3CA, PIK3R1, PLCG1, PTPN11, SHC1, ZAP70