Symbol rating rank comp degree description ADAM17 2.433156572421754 898 1 3 ADAM metallopeptidase domain 17 TNF 3.538259797344707 211 1 4 tumor necrosis factor IL6R 3.5633509449762633 201 1 4 interleukin 6 receptor STAT3 4.041596160648551 43 1 3 signal transducer and activator of transcription 3 IL6 3.9827887357432403 65 1 4 interleukin 6 JAK1 3.863301263065065 111 1 7 Janus kinase 1 IL1B 3.6167423994082415 189 1 3 interleukin 1 beta IL12A 3.7292397498260117 149 1 2 interleukin 12A IL12B 3.746748462645213 144 1 2 interleukin 12B TLR3 2.5885952661895555 722 2 1 toll like receptor 3 TLR7 3.484348204292274 228 1 2 toll like receptor 7 TLR8 1.8537569208036266 1760 1 2 toll like receptor 8 TLR2 2.8170634096117833 552 1 1 toll like receptor 2 TLR4 2.883584104343404 512 1 1 toll like receptor 4 RIGI 2.3536600666246628 986 2 1 RNA sensor RIG-I MYD88 2.9248059811311324 487 1 4 MYD88 innate immune signal transduction adaptor IRAK1 2.9165610844732437 490 1 4 interleukin 1 receptor associated kinase 1 IRAK4 2.4486466868801267 876 1 4 interleukin 1 receptor associated kinase 4 NFKBIA 2.838038203274182 536 1 4 NFKB inhibitor alpha NFKBIB 1.714801196927385 2021 1 4 NFKB inhibitor beta NFKB1 3.404494123142007 254 1 11 nuclear factor kappa B subunit 1 RELA 3.470007595602454 233 1 11 RELA proto-oncogene, NF-kB subunit IFIH1 1.9036403756248264 1663 2 2 interferon induced with helicase C domain 1 MAVS 2.042818875002865 1409 2 3 mitochondrial antiviral signaling protein IRF3 3.4313995242091484 246 2 15 interferon regulatory factor 3 IFNAR1 4.189817779344225 20 1 2 interferon alpha and beta receptor subunit 1 IFNAR2 4.571525042718164 8 1 2 interferon alpha and beta receptor subunit 2 TYK2 4.225285260420961 15 1 4 tyrosine kinase 2 STAT1 3.9292442379999404 87 1 3 signal transducer and activator of transcription 1 IRF9 3.7644557481724803 142 1 9 interferon regulatory factor 9 OAS1 3.1768556175332 327 1 1 2'-5'-oligoadenylate synthetase 1 OAS2 3.167705030368439 334 1 1 2'-5'-oligoadenylate synthetase 2 OAS3 3.167613833401467 335 1 1 2'-5'-oligoadenylate synthetase 3 IFNA1 3.786922772613164 135 2 1 interferon alpha 1 IFNA2 3.8963725674989313 101 2 1 interferon alpha 2 IFNA4 3.6339324385388494 176 2 1 interferon alpha 4 IFNA5 3.6536747538042795 166 2 1 interferon alpha 5 IFNA7 3.6461039066516725 171 2 1 interferon alpha 7 IFNA8 3.6279586876301897 181 2 1 interferon alpha 8 IFNA10 3.6461039066516725 171 2 1 interferon alpha 10 IFNA14 3.612262450419538 190 2 1 interferon alpha 14 IFNA16 3.6461039066516725 171 2 1 interferon alpha 16 IFNA17 3.920305669312716 93 2 1 interferon alpha 17 IFNA21 3.9002727044744385 98 2 1 interferon alpha 21 IFNB1 3.8096152753133476 130 2 1 interferon beta 1 MX1 3.202152689861206 313 1 1 MX dynamin like GTPase 1 MX2 3.174521371394724 330 1 1 MX dynamin like GTPase 2 TRAF6 3.02099718228161 416 1 4 TNF receptor associated factor 6 ADAR 3.1088674607215947 365 1 1 adenosine deaminase RNA specific MAP3K7 2.7637579417796463 585 1 7 mitogen-activated protein kinase kinase kinase 7 TAB2 2.042815186933508 1410 1 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 IKBKE 2.225239180481056 1165 2 2 inhibitor of nuclear factor kappa B kinase subunit epsilon TBK1 2.50989192142021 806 2 3 TANK binding kinase 1 MAPK8 3.002827647467231 434 1 3 mitogen-activated protein kinase 8 MAPK9 2.8623931927219837 526 1 3 mitogen-activated protein kinase 9 MAPK10 2.811508377497819 555 1 3 mitogen-activated protein kinase 10 FOS 3.02220549752939 415 1 3 Fos proto-oncogene, AP-1 transcription factor subunit JUN 3.5767753479413114 196 1 3 Jun proto-oncogene, AP-1 transcription factor subunit EIF2AK2 2.5306147326394353 786 1 1 eukaryotic translation initiation factor 2 alpha kinase 2 TRAF3 2.9334781491158957 484 2 4 TNF receptor associated factor 3 CHUK 2.6646673574549804 649 1 3 component of inhibitor of nuclear factor kappa B kinase complex IKBKB 2.7316522549669906 596 1 3 inhibitor of nuclear factor kappa B kinase subunit beta IKBKG 2.6318788386341017 686 1 3 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma MMP3 3.0927835924973524 374 1 2 matrix metallopeptidase 3 MMP1 3.0225380143345277 414 1 2 matrix metallopeptidase 1 CCL2 4.049943860210906 41 1 2 C-C motif chemokine ligand 2 CXCL8 3.9262878263120715 90 1 2 C-X-C motif chemokine ligand 8 STAT2 3.9870784630119576 64 1 3 signal transducer and activator of transcription 2 HBEGF 2.8974401468973956 503 1 2 heparin binding EGF like growth factor TNFRSF1A 2.8635717762897293 523 1 3 TNF receptor superfamily member 1A EGFR 3.6201588371670907 185 1 1 epidermal growth factor receptor IL6ST 3.3759496200718297 261 1 3 interleukin 6 cytokine family signal transducer FCGR2A 2.5955155106079593 715 3 7 Fc gamma receptor IIa SYK 3.3396229767012824 268 3 9 spleen associated tyrosine kinase PIK3CA 3.6906386168535854 157 3 1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PIK3CB 3.1033748479303687 369 3 1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta PIK3CD 2.8298544630563667 538 3 1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PIK3R1 3.549214485324 205 3 1 phosphoinositide-3-kinase regulatory subunit 1 PIK3R2 2.975278749794741 457 3 1 phosphoinositide-3-kinase regulatory subunit 2 PIK3R3 2.872878013811533 516 3 1 phosphoinositide-3-kinase regulatory subunit 3 PLCG1 4.011248414438996 55 3 1 phospholipase C gamma 1 PLCG2 3.0795440126482463 382 3 1 phospholipase C gamma 2 STING1 1.8810885425888229 1712 2 1 stimulator of interferon response cGAMP interactor 1 MAPK14 3.0776685867001645 384 3 1 mitogen-activated protein kinase 14 MAPK1 3.3894083552630523 258 3 1 mitogen-activated protein kinase 1 MAPK3 3.4160044903449553 253 3 1 mitogen-activated protein kinase 3 MAPK11 2.878720371715148 513 3 1 mitogen-activated protein kinase 11 MAPK13 2.5111991028250795 804 3 1 mitogen-activated protein kinase 13 MAPK12 2.4992180710406995 819 3 1 mitogen-activated protein kinase 12 CASP1 2.727860193573598 604 1 1 caspase 1 NLRP3 2.678724210985655 638 1 2 NLR family pyrin domain containing 3 ISG15 3.390714939282333 257 2 2 ISG15 ubiquitin like modifier