Input into eCrosstalk

Completed at Sat Apr 30 00:10:19 2022 (Asia/Shanghai), with the runtime of 55 seconds on the server side (not including the runtime on the client/user side).

An interactive table of user-defined ranked genes, with 1st column Genes for gene symbols, 2nd column Scores for gene scores. For example, take as inputs the resulting output from eCG2PG.

Output: pathway crosstalk

A network visualisation of pathway crosstalk, with genes/nodes color-coded by input gene scores. The significance (p-value) of observing the identified crosstalk by chance is 1.1e-37, as estimated by a degree-preserving node permutation test. Pathways are sourced from the KEGG database (release 101.0). Also provided is an editable PDF file for download.

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The crosstalk between pathways. Genes/nodes are color-coded by input gene scores, while interactions/edges are defined by KEGG pathways.

Figure 1: The crosstalk between pathways. Genes/nodes are color-coded by input gene scores, while interactions/edges are defined by KEGG pathways.

An interactive table of pathway crosstalk genes, with the column Scores for input gene scores. Genes are cross-referenced and hyperlinked to GeneCards.